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Silenor (doxepin): Online prescriptions for depression, anxiety, and sleep disorders

Silenor (doxepin) is a tricyclic antidepressant used to treat sleep-related issues, anxiety, and depression. Licensed psychiatric providers at Talkspace can evaluate your symptoms over video and provide an online doxepin prescription if appropriate, with the option to fill it locally or through Amazon Pharmacy delivery.

An initial evaluation by a Talkspace psychiatric provider is required before medication is prescribed. If appropriate, medication will be prescribed for home delivery or for pickup at your local pharmacy. Medication prices are not included in the evaluation price. Talkspace psychiatric providers are unable to prescribe controlled substances and stimulants.

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Here’s how it works

Schedule a video assessment

Answer a few questions online, then meet virtually with a psychiatric provider within a week. Appointments covered by insurance are available for members 18 and older.

Get a diagnosis and prescription

During the appointment, your Talkspace provider will listen to and evaluate your symptoms and, if appropriate, prescribe medication. Build a plan together that feels right.

Begin treatment

Your prescription will be sent to your pharmacy, and you'll have follow-up appointments with the same psychiatric provider. 

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Is Silenor (doxepin) right for you?

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What is Silenor (doxepin) used for?

Silenor (or its generic form, doxepin) is primarily used to treat insomnia. In low doses, it’s specifically prescribed for sleep-related issues. In higher doses, doxepin is used to address symptoms of anxiety and depression. By influencing brain neurotransmitters, doxepin helps restore emotional balance and improves sleep quality, with the dosing adjusted based on individual needs and the condition being treated.

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Who shouldn't take Silenor (doxepin)?

Doxepin isn't recommended for people who:

  • Have untreated narrow-angle glaucoma
  • Have severe urinary retention
  • Have taken an MAOI within the past 14 days
  • Have a known hypersensitivity to doxepin

What are the side effects of Silenor (doxepin)?

Common doxepin side effects include:

  • Dizziness
  • Drowsiness
  • Constipation
  • Dry mouth
  • Difficulty urinating
  • Nausea or vomiting
  • Sweating
  • Change in taste
  • Weight changes
  • Blood pressure changes

While these side effects are usually mild, if you notice any severe reactions or experience symptoms like confusion, blurry vision, rapid heart rate, or severe drowsiness, contact your healthcare provider right away. Always follow your doctor’s instructions and report any unexpected changes in your health.

You may experience side effects when you first begin taking doxepin that lessen or dissipate once you’ve been taking it for several weeks or months. Treatment results may vary by individual.

Meet the Talkspace licensed providers

Our network of therapists and psychiatric providers have specialization in 150+ conditions, treatment approaches, and mental health needs.

Meet the Talkspace licensed providers

Our network of therapists and psychiatric providers specialize in 150+ mental health conditions and treatment approaches. Get online therapy and medication management on one platform with ongoing care

Depression
Relationships
Anxiety & Stress
Parenting
LGBTQIA+
Chronic Illness
Eating Disorders
OCD
Anger Management
childhood abuse
Mood Disorders
trauma & Grief
Loneliness
Family Conflict
And more...
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Licensed Talkspace provider Elizabeth Keohan, LCSW-C

Elizabeth Keohan, LCSW-C

Licensed Talkspace provider Jill Daino, LCSW-R

Jill Daino, LCSW-R

Chief Medical Officer at Talkspace, Nikole Benders-Hadi

Nikole Benders-Hadi, MD, CMO

Medications we prescribe online

Talkspace psychiatric providers diagnose and treat a wide variety of mental health conditions, including anxiety, depression, ADHD, and others. For some people, their treatment involves medication. Your provider can prescribe you medication if appropriate for your treatment.
Note: Talkspace does not prescribe controlled substances.

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“I found a great therapist on Talkspace and she's noticed that I might be needing some help from a psychiatrist, so she placed a referral. I was able to see a psychiatric ARNP via video visit the next day! I'm definitely on my way to feeling better.

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See a provider today to get a new Silenor (doxepin) prescription or refill

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Any questions?

Find trust-worthy answers on all things mental health at Talkspace.

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Do you need a prescription for Silenor (doxepin)?

Yes, Silenor (doxepin) requires a valid prescription from a licensed healthcare provider to ensure its safe and effective use for your condition.

Can I get Silenor (doxepin) online?

Yes, you can get a Silenor (doxepin) prescription online from Talkspace. After a thorough virtual consultation with a licensed psychiatrist and if Silenor is deemed appropriate for your symptoms, a prescription will be provided.

What is Silenor (doxepin)?

Silenor is the brand name for the generic drug doxepin, an FDA-approved prescription medication designed to treat insomnia, anxiety, and depression. As a low-dose tricyclic antidepressant (TCA), Silenor works by regulating brain activity to improve sleep quality and promote emotional well-being. With personalized treatment, Silenor can help restore balance so you can feel better mentally and physically.

Can I get Silenor (doxepin) over the counter?

No, Silenor (doxepin) is not available over the counter (OTC). Due to the potential side effects and the need for proper medical supervision during treatment, it requires a prescription from a licensed healthcare provider.

What is Silenor (doxepin) used to treat?

In low doses, Silenor (doxepin) can treat insomnia. At higher doses, it’s also used to treat symptoms of anxiety and depression.

Can I get a new prescription or prescription refill for Silenor (doxepin) from Talkspace?

Yes, Talkspace psychiatric providers are authorized to prescribe and refill medications like Silenor (doxepin) to address insomnia, anxiety, and depression, following a thorough virtual consultation.

Can I use my health insurance for online Silenor (doxepin) prescriptions and refills?

Yes, most major health insurance plans cover online prescriptions and refills for Silenor (doxepin). Talkspace accepts a variety of insurance providers for psychiatric care and medication management, including:

Be sure to check with your insurance plan to confirm specific coverage and details about the cost of your prescription.

How much does Silenor (doxepin) cost?

The price of Silenor (doxepin) can vary depending on your location, dosage, insurance coverage, and whether you opt for the brand-name or generic version. With the use of discount cards, the cost can be under $55 per month. Always consult your pharmacist or insurance provider for exact pricing.

How do you take Silenor (doxepin)?

Silenor (doxepin) is taken orally, typically once daily on an empty stomach. For insomnia, it is taken within 30 minutes of bedtime. For anxiety or depression, your doctor may prescribe a divided dose throughout the day, depending on your treatment plan.

What antidepressant is similar to Silenor (doxepin)?

Trazodone is a similar antidepressant to Silenor (doxepin). Both medications are commonly used to treat conditions like insomnia and depression. 

While doxepin is often prescribed for its sedative effects to treat sleep problems, Trazodone is also commonly used to help with sleep while treating depressive symptoms. Each medication has unique properties, so it's important to consult with a healthcare provider to determine which option is best for your needs.

Disclaimer
Talk to your psychiatrist or healthcare professional about the possible risks and benefits associated with the above medications before starting treatment. It’s up to your psychiatric clinician’s professional judgment whether medication is prescribed. If you are in a life threatening situation – don’t use this site. Call +1 (800) 273-8255 or use these resources to get immediate help.